Prilosec vs Nexium. Which is better?
Prilosec vs Nexium. Which is better?
Psychologic well-being questionnaires have found that patients with GERD can have a worse quality of life than some patients with menopausal symptoms, peptic ulcer disease, angina or congestive heart failure. The combination of symptoms, dietary restrictions and functional limitations can take a toll on overall sense of well-being. But Omeprazole (Prilosec) and Esomeprazole (Nexium) can reduce its symptoms.
Gastroesophageal reflux disease, or GERD, occurs when the lower esophageal sphincter (LES) does not close properly and stomach contents leak back, or reflux, into the esophagus. The LES is a ring of muscle at the bottom of the esophagus that acts like a valve between the esophagus and stomach. The esophagus carries food from the mouth to the stomach.
When refluxed stomach acid touches the lining of the esophagus, it causes a burning sensation in the chest or throat called heartburn. The fluid may even be tasted in the back of the mouth, and this is called acid indigestion. Occasional heartburn is common but does not necessarily mean one has GERD. Heartburn that occurs more than twice a week may be considered GERD, and it can eventually lead to more serious health problems. The main symptoms are persistent heartburn and acid regurgitation. Some people have GERD without heartburn. Instead, they experience pain in the chest, hoarseness in the morning, or trouble swallowing. You may feel like you have food stuck in your throat or like you are choking or your throat is tight. GERD can also cause a dry cough and bad breath.
Nexium is used to treat gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and injury of the esophagus (food pipe between the mouth and stomach). Nexium is used to treat the symptoms of GERD, allow the esophagus to heal, and prevent further damage to the esophagus. Nexium is in a class of medications called proton pump inhibitors. It works by decreasing the amount of acid made in the stomach. Prilosec (Omeprazole) is used to treat various acid-related stomachs and / or throat (esophagus) problems (e.g., GERD, ulcers, erosive esophagitis, or Zollinger-Ellison Syndrome).
Prilosec vs Nexium comparison table
How Prilosec and Nexium are taken
|Prilosec is a delayed-release 20mg tablet, taken once a day (every 24 hours) for 14 days before eating. You should not take it for more than 14 days or repeat a 14-day course more often than every 4 months unless directed by a doctor. Do not crush, break, or chew the tablet. This decreases how well Prilosec works in the body.||Nexium comes as a delayed-release (long-acting) capsule to take it orally. It is usually taken once a day at least one hour before a meal. To help you remember to take Nexium, take it around the same time every day. Swallow the capsules whole; do not split, chew, or crush them.|
Possible Prilosec and Nexium Side Effects
|Include headache, constipation, cough, or diarrhea. An allergic reaction to Nexium is unlikely, but seeks immediate medical attention if it occurs. May cause diarrhea, constipation, stomach-ache, nausea, and gas, loss of appetite, headache, or dizziness the first few days as your body adjusts to it. This medication may rarely cause loss of hair, ringing in the ears, swelling of the stomach or fatigue. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention.||Include headache, constipation, cough, or diarrhea. An allergic reaction to Nexium is unlikely, but seeks immediate medical attention if it occurs.|
Prilosec and Nexium affect on pregnancy
|Safety for use during pregnancy has not been established.||Safety for use during pregnancy has not been established. It is not known whether Nexium passes into breast milk.|
Prilosec and Nexium precautions
|Bioavailability may increase||Symptomatic relief with proton pump inhibitors may mask symptoms of gastric malignancy|
In the case of overdosing doctors recommend, for both Nexium and Prilosec, to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.
As you can see from the table, these medicines are practically having quite different influence on the human organism. In spite of causing some site effects, there are, of course several restrictions for using it. For example, you shouldn’t use Nexium if you have a history of penicillin hypersensitivity and/or a history of sensitivity to multiple allergens. Otherwise, it can produce serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients on penicillin therapy. Pseudo membranous colitis has been reported with nearly all antibacterial agents, including clarithromycin and amoxicillin, and may range in severity from mild to life threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents. As for the Prilosec, it is not appropriate if you:
-have only occasional heartburn
-have one episode of heartburn a week or less
-want immediate relief of heartburn.
Of course there is no single therapy that can be better than any other. But from the experience of treating hundreds of patients with moderate to severe heartburn, most patients will do equally as well on 20 mg of Prilosec and 40 mg of Nexium. They think that Nexium is slightly more effective than Prilosec; however, not many patients will require stronger medications. So it is for you and your doctor to decide which medicine will suit you the most.
Go follow these links to read more information about Nexium and Prilosec medications.